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Melatonin XL 2 mg – Prolonged-Release Tablets

Melatonin XL 2 mg – Prolonged-Release Tablets

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  • Prolonged-release formulation designed for overnight support
  • Supports the body’s natural circadian rhythm
  • Commonly used for difficulty staying asleep
  • Non-sedative and non-habit forming when used as directed
  • Supplied following clinical assessment
  • UK-regulated pharmacy service

Melatonin XL 2 mg – Prolonged-Release Tablets

Category:Sleep Help (Insomnia)

Melatonin XL 2 mg is a prolonged-release melatonin tablet used to support the body’s natural sleep–wake cycle in adults experiencing insomnia, particularly where difficulty staying asleep is a concern.

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Frequently Asked Questions for Melatonin XL 2 mg – Prolonged-Release Tablets

Who May Be Suitable

Melatonin XL may be considered for adults with:

  • Difficulty staying asleep
  • Disrupted sleep–wake cycles
  • Circadian rhythm disturbance
  • Age-related changes in sleep patterns

All patients must complete an online consultation before treatment can be supplied.

My London Pharmacy Sleep Clinic

My London Pharmacy provides access to a Sleep Clinic for patients experiencing ongoing sleep difficulties.

Following your online consultation, a clinician will assess your symptoms and medical history. If melatonin is not the most suitable option, or if additional support is needed, you may be eligible for alternative treatment options following clinical review.

Dosage and Use

  • Take one tablet in the evening, usually 1–2 hours before bedtime
  • Swallow whole; do not crush or chew
  • Use only as directed by your clinician

Possible Side Effects

Melatonin is generally well tolerated. Some patients may experience:

  • Headache
  • Dizziness
  • Nausea
  • Daytime drowsiness

Side effects are usually mild and temporary.

Important Safety Information

  • Do not use if you are allergic to melatonin or any ingredients
  • Not recommended during pregnancy or breastfeeding unless advised by a clinician
  • Use caution if taking antidepressants, sedatives, or anticoagulants
  • Avoid alcohol while taking melatonin
  • Not intended for long-term continuous use without clinical review

Always provide full medical and medication history during your consultation.


NICE Guidance

Prolonged-release melatonin is recognised within UK clinical practice for selected patients with insomnia.

Further information can be found at:

https://www.nice.org.uk