Ryaltris

Ryaltris is a clinically proven prescription nasal spray used to treat:

• Seasonal allergic rhinitis including hay fever
• Perennial allergic rhinitis (year-round nasal allergy symptoms)
• Persistent nasal congestion and blockage caused by allergies
• Sneezing, nasal itching, and runny nose from allergic reactions
• Sinus pressure and inflammation related to allergic rhinitis
• Moderate to severe nasal allergy symptoms uncontrolled by single-ingredient treatments

Ryaltris is a combination prescription nasal spray that brings together two complementary active ingredients in a single convenient spray. Azelastine hydrochloride is an antihistamine that provides rapid relief from sneezing, itching, and runny nose by blocking histamine receptors. Mometasone furoate is a corticosteroid that reduces nasal inflammation and helps relieve congestion and sinus pressure over time. Together they address both the immediate and underlying inflammatory aspects of allergic rhinitis, making Ryaltris a more comprehensive treatment option than either ingredient alone. It is commonly recommended as a second-line treatment for patients whose allergy symptoms remain uncontrolled with standard nasal sprays.

Ryaltris works through two complementary mechanisms delivered directly to the nasal passages. Azelastine hydrochloride blocks H1 histamine receptors in the nasal lining, rapidly reducing the histamine-driven symptoms of sneezing, itching, and watery discharge that are triggered by exposure to allergens such as pollen, dust mites, or pet dander. Mometasone furoate simultaneously reduces inflammation in the nasal passages by suppressing the release of inflammatory chemicals involved in the allergic response, providing sustained relief from congestion and sinus pressure. This dual approach addresses both the fast-onset symptoms and the underlying nasal inflammation that drives persistent allergic rhinitis.

For adults and adolescents aged 12 years and over:

• One spray into each nostril twice daily
• Shake the bottle gently before each use
• Clear the nose before applying
• Spray while breathing in gently through the nose
• Avoid spraying directly onto the nasal septum
• Use regularly every day for best results, even if symptoms begin to improve

Ryaltris is generally well tolerated. Common side effects may include:

• Nosebleeds
• Headache
• Bitter or unpleasant taste following use
• Nasal irritation or dryness

Rarely, prolonged use may increase the risk of nasal ulceration or fungal infection in the nasal passages. Always use as prescribed and consult a healthcare professional if side effects persist or worsen.

For nasal use only: Ryaltris is designed exclusively for nasal administration and should not be swallowed or used in the eyes.

Do not exceed the prescribed dose: Overuse of corticosteroid nasal sprays can increase the risk of systemic side effects over time.

Other corticosteroids: Inform your prescriber if you are already using other corticosteroid medications, including inhalers or skin creams, as combined use may increase systemic exposure.

Nasal infections or recent surgery: Do not use Ryaltris if you have an untreated nasal infection or have recently undergone nasal surgery until you have been cleared by a healthcare professional.

Pregnancy and Breastfeeding: Ryaltris should only be used during pregnancy or breastfeeding under direct medical supervision. Speak to your GP or pharmacist for advice.

Children under 12: Ryaltris is not recommended for children under 12 years of age. It is suitable for adolescents aged 12 and over as prescribed by a GP.

Driving: Ryaltris is not expected to affect the ability to drive. However, if you experience drowsiness consult your prescriber.

What makes Ryaltris different from standard allergy nasal sprays? Most nasal sprays contain either an antihistamine or a corticosteroid. Ryaltris combines both in a single spray, targeting multiple allergy pathways at once. This makes it more effective for moderate to severe symptoms and for patients who have not had sufficient relief from single-ingredient treatments.

How quickly does Ryaltris work? Some symptom relief from the antihistamine component can be noticed within hours of the first dose. The full anti-inflammatory benefit of the corticosteroid component typically develops after several days of regular use. Consistent daily use is important for best results.

Is Ryaltris a steroid nasal spray? Yes. Ryaltris contains mometasone furoate, a well-established corticosteroid, alongside azelastine hydrochloride, an antihistamine. The steroid component is delivered locally to the nasal passages, minimising systemic absorption when used as directed.

Can Ryaltris be used for hay fever? Yes. Ryaltris is clinically indicated for seasonal allergic rhinitis including hay fever, as well as perennial allergic rhinitis for year-round allergy sufferers.

Can Ryaltris be used long-term? Yes, when prescribed and monitored by a healthcare professional. Long-term use should always be reviewed periodically by your prescriber to ensure ongoing suitability.

Is Ryaltris suitable for children? Ryaltris is not recommended for children under 12 years of age. It is suitable for adolescents aged 12 and over when prescribed by a GP.

Can I use Ryaltris alongside other allergy medications? You should inform your prescriber of all other medications you are taking, particularly other corticosteroids or antihistamines. Our prescribers will assess suitability during your online consultation.

Do I need a prescription to order Ryaltris? Yes. Ryaltris is a prescription-only medicine in the UK. A prescription is included in the price of your order following a short online consultation with our UK-registered prescribers at no additional charge.

Will Ryaltris work if I have tried other nasal sprays before? Ryaltris is specifically recommended for patients whose symptoms have not been adequately controlled by single-ingredient nasal sprays. Its dual-action formula makes it a stronger and more comprehensive option for persistent or moderate to severe allergic rhinitis.